Yeast Extract for Biopharma Cell Culture

ART-MN-027 is an inactivated yeast extract designed for fermentation nutrition and biopharma cell culture media development. It provides a complex nutrient profile containing peptides, free amino acids, B-group vitamins naturally associated with yeast biomass, nucleotides, minerals, and soluble carbohydrate fractions. The product is not a live yeast and is not intended for leavening or direct inoculation; it functions as a soluble feed component for upstream media, seed-train support, and process optimization.

Typical specification targets for this grade may include moisture not more than 6.0%, total nitrogen 10.0-12.5%, amino nitrogen 4.5-6.5%, protein equivalent 62-78%, ash 8-15%, pH 5.0-7.0 in a 2% aqueous solution, and fine powder through approximately 80 mesh, subject to confirmed lot data. Color is generally light yellow to tan with characteristic yeast extract odor. For related inputs, see the microbial nutrition fermentation category. Bulk quote on request is available for qualified buyers evaluating ART-MN-027 against internal media performance criteria.

• Biopharma upstream media: organic nitrogen and peptide source for cell culture media, process development media, feed solutions, and non-defined media systems where a yeast-derived complex nutrient is acceptable.
• Industrial fermentation: nutrient input for bacteria, yeast, and filamentous organisms used in enzyme, organic acid, amino acid, vitamin, and specialty metabolite production.
• Seed and inoculum expansion: supports robust early-stage growth by contributing soluble amino nitrogen, minerals, and micronutrients for propagation steps prior to production fermentation.
• R&D screening: suitable for design-of-experiment work comparing yeast extract inclusion rate, nitrogen contribution, heat treatment, pH adjustment, and compatibility with defined salts, sugars, and trace elements.
• Procurement standardization: available as ART-MN-027 in 20 kg multi-wall sacks for facilities that require SKU-level traceability, repeat ordering, and documented lot review before plant release.

Store unopened sacks in a clean, dry, odor-free warehouse at 5-25 °C, protected from moisture, direct sunlight, and strong oxidizing materials. Recommended relative humidity is below 65% to reduce caking risk. Keep product sealed after opening and use hygienic dispensing tools to avoid foreign matter introduction. Under recommended conditions, typical shelf life is 24 months from manufacture, subject to the certificate of analysis and packaging integrity.

ART-MN-027 is supplied as a dry, hygroscopic powder and should be handled in areas with appropriate dust control. It is normally dissolved in purified or process water with agitation; formulators should validate solubility, heat stability, filtration behavior, osmolality contribution, and compatibility with their complete media system. The material is not sterile as supplied unless otherwise agreed in writing. Users should apply validated sterilization, filtration, or heat-treatment steps required by their own process controls. To discuss sack count, pallet configuration, or a bulk quote on request, contact ArtemisYeast with the ART-MN-027 SKU and target annual volume.

ArtemisYeast supplies ART-MN-027 for industrial and research manufacturing environments where purchasing teams require predictable documentation before approval. Lot-specific certificate of analysis can be provided on request, covering key chemical and physical parameters such as moisture, nitrogen profile, ash, pH, appearance, and microbiological indicators where included in the agreed specification. Food-grade declaration, allergen statement, country-of-origin statement, non-GMO statement, and safety data sheet can be requested for supplier qualification packages.

Manufacturing is managed under supplier quality systems aligned with HACCP principles and documented batch traceability. ISO 22000, FSSC 22000, Halal, Kosher, or other food-safety documentation may be available on request depending on production site and lot; ArtemisYeast will confirm current document status during quotation and before purchase order acceptance. For supplier audits, specification review, and import documentation expectations, use the quality documentation channel so technical and procurement teams can review requirements before shipment.